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Beilstein J. Org. Chem. 2017, 13, 1518–1523, doi:10.3762/bjoc.13.151
Graphical Abstract
Figure 1: Brominating reagents.
Scheme 1: Optimization of the substituents of the amide group. Reactions were run using 1 (0.1 mmol), 3a (0.0...
Scheme 2: Substrate scope. Reactions were run using 1 (0.1 mmol), 3a (0.01 mmol), and 4a (0.3 mmol) in EtOAc ...
Scheme 3: Reactions of substrates with substituted phenols.
Scheme 4: Reactions of monobrominated substrates.
Scheme 5: Rotational barriers of substrates and intermediates calculated at the B3YLP/6-31G(d) level of theor...
Scheme 6: Reaction of substrate with protected phenol.